Health & Medicine Episodes

The CDC issued six health alerts in all of 2025, down from dozens in a normal year, whatever that means anymore. Measles, a disease we basically eliminated 26 years ago, is closing in on 1000 cases, with children hospitalized for brain swelling. And the people now running our top health agencies are the same people who spent years questioning the science those agencies existed to defend. But the good news is people are building new things. States are forming their own health alliances. Scientist...

If our mission is to help people, everyone, answer the most important question, what can I do? Then at some point we need to talk to the people who help really wealthy people, help people. So today's question, what can I do about high net worth philanthropy? And look, hey, maybe you're among the vast majority who just heard that and you're like, well, this one doesn't apply to me, but hear me out. We have some of the worst billionaires of all time, but if billionaires are gonna continue to exist...

Hey friends, I want to talk about something big. Change the actual world big, because the world won't unfuck itself, as we all know. We are joining podcasts across the planet for Pods Fight Poverty , a campaign directly supporting our good friends at Give Directly . Now, if you've been with us since episode 116 , which feels like a thousand years ago, you'll remember when we asked one of the most deceptively simple, world altering questions ever. Why is just giving people money the most effectiv...

What if talking about menopause out loud was as normal as talking about sports scores or school pickup? Imagine it in movie plots, in your group chat, at the clinic, and on the campaign trail because when we name what's happening in our bodies, three things can follow: better care, better research, and better policy. Normalizing the conversation around something that's gonna happen to half the population isn't oversharing. It's infrastructure. This is how we're gonna get appointments that move t...

Chronically parched is not something anyone in this country or anywhere should ever have to feel, but here we are. So how are towns and states making clean water more affordable, reliable, and less controversial? 'cause remember, it's fucking water. Look, you might feel like you're giving it all you got but when you look around things are a little dark out there. So you, our listeners and readers and viewers and users, whatever, across the world, want and demand more examples of fight and progre...

Maybe you feel like you're already giving it all you've got. You look around, and things are tough out there. You, our listeners and readers and viewers and users across the country and across the world, you're demanding more examples of fight and progress you can actually see and touch and feel, and in these conversations, in this series, in partnership with our very best friends at Run For Something, we're gonna give you exactly what you asked for. Each of these episodes features two guests, b...

In a moment when the news out of Washington can seem untenably rough, when the gerontocracy that got us here won't give up their hold on power, when billionaires own every single media channel, when everything from housing to childcare to elderly care and healthcare have been made unaffordable, if accessible at all, and the question, what can I do? Can feel more fruitless than ever, I come bearing good news. Look to the young people. Look to our school boards, our cities, and in many cases to ou...

Turns out it's our 200th episode. It has been a journey. The show is now called The Most Important Question, and I can't think of a better answer than just fucking run for something. What can I do about anything? Run for something. And so obviously the best guest to answer that question, is returning guest, Amanda Litman . If you are new here, she is the co-founder and president of Run For Something, which recruits and supports young, diverse progressives running for down-ballot office, state an...

Imagine waking up to discover that the United States has just pulled $35 billion out of foreign aid overnight, and that hundreds of HIV clinics, and child malnutrition programs, and poverty graduation trials will shut their doors within days and weeks. Now imagine there's a rapid response team quietly sifting through every single grant, ranking them by lives saved per dollar and building lifeboat bridge grants before the lights go out. That team exists. It's called Project Resource Optimization ...

63% of Americans say abortion should be legal in all or most cases, and yet here we are. So what can we do to make the language around abortion more positive? My guest today is Sophie Nir . Sophie is the CEO of the Abortion Positivity Project . The Abortion Positivity Project seeks to destigmatize abortion by more or less overhauling the framework by which we currently understand and discuss it. They've developed a training curriculum on embracing abortion positive messaging in partnership with ...

We've spent the last few years learning up close how a crisis like a global pandemic reveals and deepens all of our faults, inequalities, biases, and outright failures of empathy. But here's the kicker: it's not the first time. Plagues and epidemics have always shown us who we really are. And they've left footprints, good and bad, on our institutions and the stories we tell ourselves. So why do we keep missing the lessons? My guest today is Edna Bonhomme , a historian, author, and public health ...

One of the ways this Trump administration is different from the last is, relatively at least, how much more unconstitutional, how much more organized and comprehensive the attacks on our institutions, particularly the scaffolding we built for ourselves the most precious parts of of our societies: immigration, agriculture, the VA, NIH, the CDC, the NSF and humanitarian work around the globe. Do some of these need reform? Of course, they do. Is this the way to do it? No, it is not. These instituti...

What can we do about land power? It's the most important question and my guest today is Mike Albertus . Mike is a professor of political science at the University of Chicago . He's the author of the new book, Land Power . Who has it? Who doesn't? And how that determines the fate of societies. In the book, Mike examines how land became power, how it shapes power today still, and how who holds that power determines the fundamental social problems that societies grapple with. Mike studies how count...

We (Quinn) has been avoiding this question for quite a while. I even wrote a few thousand words about it a couple months ago and didn't publish it because it was a bit of a downer. But that's kind of malpractice in a way because we promised we don't shy away from the hard stuff even if the goal is to help you understand what you can do about it. Just like there's never really an optimal time in your life to get married, or have a baby, or get arrested, there's never a good time to talk about bir...

What's the missing link in local journalism? That's today's big question, and my guest is Lyndsey Gilpin . Lyndsey is the Senior Manager of Community Engagement at Grist. Lyndsey was the founder and executive editor at Southerly , a nonprofit media organization that equipped people who face environmental injustices and are at most at risk of climate change effects with journalism and resources on natural disasters, pollution, food, energy, and more. It was very groundbreaking, and now she's brou...

Is multisolving the future? Is it today? Should we do more? That's all today's big question and my guest is Dr. Elizabeth Sawin . Dr. Sawin is the Founder and Director of the Multisolving Institute , which is convenient for our conversation. She's an expert on solutions that address climate change while also improving health, well being, and economic vitality. She developed multisolving to describe such win win win solutions. Beth writes and speaks about multisolving, climate change, and leaders...

There’s no word for “conservation” in many Indigenous languages. Some come close, but mean something more like “taking care of” or “looking after.” And that’s probably because the very idea of conservation, to “prevention the wasteful use of a resource”, would have been, and continue to be, foreign to many of North America’s Indigenous peoples, who lived in an entirely different, co-dependent relationship with nature. That is to say, to have had a relationship at all. A relationship with the ver...

How do we tackle huge systemic intersectional environmental justice issues at the local level? That's today's big question, and my guest is Jacqui Patterson . Jacqui is the Founder and Executive Director of the Chisholm Legacy Project , which helps connect Black communities that are being disproportionately impacted by the climate crisis with the resources they need to create systemic change across connected challenges. Jacqui was recently named to Time Magazine's 2024 list of Women of the Year ...

How do we take a huge chronic disease burden like Lyme disease or long COVID or even long flu and make it so personal that we simply can't ignore it anymore? That's today's big question and my guest is Dr. Mikki Tal , an immunoengineer and a principal scientist at MIT. Dr. Tal leads the Tal Research Group within the Department of Biological Engineering , and also serves as the Associate Scientific Director of the Center for Gynepathology Research . Mikki is working to identify the connections be...

Who is still covering Long COVID, and how much is the audience actually growing? That's today's big question, and my guests are Betsy Ladygetz and Miles Griffis , editors and co-founders of The Sick Times , a journalist-founded website chronicling the Long COVID crisis. The Sick Times investigates injustices, challenges powerful institutions, wades through the latest research, assesses COVID-19 data, and offers an essential platform for those most affected by the crisis. Betsy is an independent ...

What have we learned from millennia of water insecurity, of climate changes and disasters, of building along freshwater ways and the ocean, that we can apply today? That's today's big question, and my guest is Dr. Amber Wutich . Dr. Wutich is an ASU President's Professor , Director of the Center for Global Health , and 2023 MacArthur Fellow. She's an expert on water insecurity, and directs the Global Ethnohydrology Study , a cross cultural study of water knowledge and management in over 20 count...

You know you're stressed. You know you're anxious. Do you have depression? And do you need to know the latest in the biology of how the brain works and depression works or doesn't work and whether the gut is involved in getting meaningful help? That's today's big question. I promise it's kind of one question, even if there are a ton of different answers, and they're going to be different for everybody. This conversation is a follow-up to our last couple of conversations about the brain, the gut,...

What are reverse coattails, and how might they slow climate change, prevent the next pandemic, and keep Nazis off of school boards? That's today's big question, and my returning guest is Amanda Litman . Amanda is one of my favorite people. She is the co-founder and co-executive director of Run for Something , which recruits and supports young, diverse progressives running for down-ballot office, state, and local, and all those fun levels. Since launching in 2017 , a thousand years ago, Run for S...

How do we get our attention back? That's today's big question. I think about it every day, and my guest is Johann Hari . Johann and I recorded this conversation in 2022 , and with the Internet in general and social networks of the past fifteen years being straight-up pulled apart, I think it's more relevant than ever. Johann Hari is the author of three New York Times best-selling books, an executive producer of an Oscar-nominated movie, and an eight-part series starring Samuel L. Jackson . His b...